Encounter with sex steroid hormone therapy in severe preeclampsia (No2):

Blood Sex steroid hormone (estradiol and progesterone) levels in pregnant
women are enormously increased at late stage of pregnancy compared with
those in non-pregnant women.




Female sex hormone is estradiol and progesterone.  Estrogen is secreted
from ovary and its level in blood is increased at maximum just before
ovulation in women suggesting that this hormone is essential for ovum
maturation. Progesterone is secreted just after ovulation and its level in
blood is increased at maximum around 7 day after ovulation suggesting
that this hormone is essential for implantation of ovum: beginning and
continuation of pregnancy. Among estrogen hormones estradiol is the
most bioactive hormone.

Blood estradiol levels in pregnant women
 increase with advancing gestation.  Estradiol levels reach to their
maximum level at late pregnancy. The magnitude of the increase of
estradiol levels are around 100 fold compared with those just before
 ovulation. Blood progesterone levels in pregnant women increase also
with advancing gestation. Progesterone levels reach to their maximum
level at late pregnancy.
The magnitude of the increase of progesterone levels
are around 10 fold compared with those around 7 day after ovulation.