As being an honorary member of The Endocrine Society, I periodically receive “Endocrine News” produced by the Society.


In April 2016 newsletter, I have found an article titled “Correct Change”. The following sentences appeared: Hormone therapy (HRT) remains the most effective treatment for the vasomotor and other symptoms of menopause, expert panel from the Endocrine Society and allied organizations concluded in a new clinical practical guideline.

Allied organizations are follows: Australasian Menopause Society, British Menopause Society, European Menopause and Andropause Society, European Society of Endocrinology and International Menopause Society.


HRT had been a common practice before the initial findings of the Women’s Health Initiative which appeared 13 years ago.

In other words, HRT has been averted by the clinicians worldwide. In spite of such an environment, I continued HRT at my clinic under somehow inconvenient atmosphere. It is because I have my solid belief: HTR is not the cause of breast cancer and not the cause of thrombosis either (see my previous blog on May 5, 2016). (http://p-lap.doorblog.jp/archives/48289432.html)


After my long research experiences on pathophysiology of preeclampsia, now I have the following concept: While estradiol is the active agent for inducing angiotensinogen and fibrinogen from liver, metabolizing and degrading enzymes opposed to the estradiol actions are also activated in human body. If we assume HRT is carcinogenic, every woman should suffer from cancers. Women’s health is maintained by sex hormones.

Therefore, oral contraceptive pills and HRT must be welcomed by all women no matter where in the world she may live.